(3S)-3-(9H-Fluoren-9-Ylmethoxycarbonylamino)-5-Oxo-5-[Tri(Phenyl)Methylamino]Pentanoic Acid
Fmoc-L-beta-homoasparagine(Trt)
CAS: 283160-20-3
Molecular Formula: C39H34N2O5
(3S)-3-(9H-Fluoren-9-Ylmethoxycarbonylamino)-5-Oxo-5-[Tri(Phenyl)Methylamino]Pentanoic Acid - Names and Identifiers
| Name | Fmoc-L-beta-homoasparagine(Trt) |
| Synonyms | Fmoc-β-HoAsn(Trt)-OH FMOC-BETA-GLN(TRT)-OH FMoc-beta-HAsn(Trt)-OH FMOC-BETA-HOASN(TRT)-OH FMOC-ASN(TRT)-(C*CH2)OH fmoc-b-Homoasparagine(trt) Fmoc-L-beta-Homo-Asn(Trt)-OH FMOC-L-BETA-HOMOASPARAGINE(TRT) Fmoc-L-beta-homoasparagine(Trt) FMOC-GAMMA-TRITYL-L-BETA-HOMOASPARAGINE (3S)-3-{[(9H-fluoren-9-ylmethoxy)carbonyl]amino}-5-oxo-5-(tritylamino)pentanoic acid (3S)-3-(9H-Fluoren-9-Ylmethoxycarbonylamino)-5-Oxo-5-[Tri(Phenyl)Methylamino]Pentanoic Acid (3S)-3-(9H-Fluoren-9-ylmethoxycarbonylamino)-5-oxo-5-[tri(phenyl)methylamino]pentanoic acid |
| CAS | 283160-20-3 |
| EINECS | 689-323-1 |
| InChI | InChI=1/C39H34N2O5/c42-36(41-39(27-14-4-1-5-15-27,28-16-6-2-7-17-28)29-18-8-3-9-19-29)24-30(25-37(43)44)40-38(45)46-26-35-33-22-12-10-20-31(33)32-21-11-13-23-34(32)35/h1-23,30,35H,24-26H2,(H,40,45)(H,41,42)(H,43,44)/t30-/m0/s1 |
(3S)-3-(9H-Fluoren-9-Ylmethoxycarbonylamino)-5-Oxo-5-[Tri(Phenyl)Methylamino]Pentanoic Acid - Physico-chemical Properties
| Molecular Formula | C39H34N2O5 |
| Molar Mass | 610.7 |
| Density | 1.256 |
| Boling Point | 873.4°C at 760 mmHg |
| Flash Point | 482°C |
| Vapor Presure | 1.3E-32mmHg at 25°C |
| Storage Condition | Sealed in dry,2-8°C |
| Refractive Index | 1.636 |
| MDL | MFCD03427579 |
(3S)-3-(9H-Fluoren-9-Ylmethoxycarbonylamino)-5-Oxo-5-[Tri(Phenyl)Methylamino]Pentanoic Acid - Risk and Safety
| WGK Germany | 3 |
| FLUKA BRAND F CODES | 10 |
| Hazard Class | IRRITANT |
(3S)-3-(9H-Fluoren-9-Ylmethoxycarbonylamino)-5-Oxo-5-[Tri(Phenyl)Methylamino]Pentanoic Acid - Introduction
Fmoc-L-beta-homoasparagine(Trt) (Fmoc-L-beta-homoasparagine(Trt)) is an organic compound with the chemical formula C38H32N2O5 and a relative molecular mass of 600.67g/mol.
The compound is mainly used for peptide synthesis in solid phase synthesis. It is an aromatic β-amino acid with good chemical stability and solubility, and can be used to establish a specific structure of the peptide chain. The valeric acid moiety provides the function of protecting the amino acid from destruction by unwanted reactions during synthesis. The fluorenylmethoxycarbonyl (Fmoc) group can be easily deprotected to further extend the synthetic peptide chain.
Fmoc-L-beta-homoasparagine(Trt) is usually prepared by synthesizing a series of intermediates to obtain the final product. In the specific preparation, the valeric acid portion of the β-amino acid is first synthesized and reacted to produce fluorenylmethoxycarbonylated valeric acid. It is then reacted with trityl amine in the presence of the corresponding reagent to form trityl amine hydrochloride. Finally, the fluorenomethoxy peptide moiety is combined with tritylamine hydrochloride to give Fmoc-L-beta-homoasparagine(Trt).
Regarding safety information, the use of Fmoc-L-beta-homoasparagine(Trt) requires attention to its toxicity and irritation. Appropriate personal protective equipment, such as lab gloves and goggles, should be worn during operation. At the same time, the operation should be carried out in a well-ventilated laboratory environment, avoiding contact with skin, eyes and inhalation. If you come into contact with this substance, rinse immediately with plenty of water and seek medical help.
The compound is mainly used for peptide synthesis in solid phase synthesis. It is an aromatic β-amino acid with good chemical stability and solubility, and can be used to establish a specific structure of the peptide chain. The valeric acid moiety provides the function of protecting the amino acid from destruction by unwanted reactions during synthesis. The fluorenylmethoxycarbonyl (Fmoc) group can be easily deprotected to further extend the synthetic peptide chain.
Fmoc-L-beta-homoasparagine(Trt) is usually prepared by synthesizing a series of intermediates to obtain the final product. In the specific preparation, the valeric acid portion of the β-amino acid is first synthesized and reacted to produce fluorenylmethoxycarbonylated valeric acid. It is then reacted with trityl amine in the presence of the corresponding reagent to form trityl amine hydrochloride. Finally, the fluorenomethoxy peptide moiety is combined with tritylamine hydrochloride to give Fmoc-L-beta-homoasparagine(Trt).
Regarding safety information, the use of Fmoc-L-beta-homoasparagine(Trt) requires attention to its toxicity and irritation. Appropriate personal protective equipment, such as lab gloves and goggles, should be worn during operation. At the same time, the operation should be carried out in a well-ventilated laboratory environment, avoiding contact with skin, eyes and inhalation. If you come into contact with this substance, rinse immediately with plenty of water and seek medical help.
Last Update：2024-04-10 22:29:15
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Product Name: (S)-3-(Fmoc-amino)-N-trityl-valeric acid 5-amide Visit Supplier Webpage Request for quotation
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Mobile: 18021002903
QQ: 3008007409
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CAS: 283160-20-3
Tel: 18301782025
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View History
(3S)-3-(9H-Fluoren-9-Ylmethoxycarbonylamino)-5-Oxo-5-[Tri(Phenyl)Methylamino]Pentanoic Acid
2-Dimethylamino-5-methyl-6-oxo-6-phenyl-2,4-hexadienoic acid ethyl ester
6-溴吲哚-3-乙酸
1-chloro-2-fluoroethane
Orient Yellow 4120
1309-56-4
2-Dimethylamino-5-methyl-6-oxo-6-phenyl-2,4-hexadienoic acid ethyl ester
6-溴吲哚-3-乙酸
1-chloro-2-fluoroethane
Orient Yellow 4120
1309-56-4